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When I was a child, there were not that many vaccines. I was vaccinated for polio. I actually got measles as a child. I got pertussis, whooping cough. I remember that very well.
Previous efforts to eradicate malaria failed for several reasons, including political instability and technical challenges in delivering resources, especially in certain countries in Africa.
The immune systems goal is to protect the body against invaders either from without, such as microbes, or from within, such as cancers and different types of neoplastic transformation.
One of the by-products of being a perfectionist and constantly trying to improve myself are sobering feelings of low-grade anxiety and a nagging sense of inadequacy This anxiety keeps me humble.
I think, collectively, we should be paying more attention to what is going on around us in the world among people who dont have the advantages that we have.
Although it is still important to develop an HIV vaccine, we have significant tools already at our disposal that can make a major impact on the trajectory of this epidemic.
There has been treatment for hepatitis C, but the treatment has not been overwhelmingly effective, number 1. And number 2, it has had considerable toxicity.
The Europeans have lots of data on the use of adjuvanted flu vaccine in the elderly, but I dont think anybody has really good data on adjuvants in children.
You can have an epidemic in a state. You can have it in a region. You can have it in a country where the critical level of disease passes a certain threshold and we call that an epidemic threshold.
We are grateful to the Liberian people who volunteered for this important clinical trial and encouraged by the study results seen with the two investigational Ebola vaccine candidates.
When a company is fairly certain of a profit margin that is substantial, it can assume responsibility for the clinical trials to develop a blockbuster drug.