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True ignorance is not the absence of knowledge, but the refusal to acquire it.
In so far as a scientific statement speaks about reality, it must be falsifiable; and in so far as it is not falsifiable, it does not speak about reality.
The best thing that can happen to a human being us to find a problem, to fall in love with that problem, and to live trying to solve that problem, unless another problem even more lovable appears.
Ignorance is not a simple lack of knowledge but an active aversion to knowledge, the refusal to know, issuing from cowardice, pride, or laziness of mind.
A theory which is not refutable by any conceivable event is non-scientific. Irrefutability is not a virtue of a theory (as people often think) but a vice.
Evolution is not a fact. Evolution doesn't even qualify as a theory or as a hypothesis. It is a metaphysical research program, and it is not really testable science.
It is the rule which says that the other rules of scientific procedure must be designed in such a way that they do not protect any statement in science against falsification.
It is not his possession of knowledge, of irrefutable truth, that makes the man of science, but his persistent and recklessly critical quest for truth.
The difference between the amoeba and Einstein is that, although both make use of the method of trial and error elimination, the amoeba dislikes erring while Einstein is intrigued by it.
The more we learn about the world, and the deeper our learning, the more conscious, specific, and articulate will be our knowledge of what we do not know, our knowledge of our ignorance
The open society is one in which men have learned to be to some extent critical of taboos, and to base decisions on the authority of their own intelligence.
It is wrong to think that belief in freedom always leads to victory; we must always be prepared for it to lead to defeat. If we choose freedom, then we must be prepared to perish along with it.