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Stress is not a state of mind... it's measurable and dangerous, and humans can't seem to find their off-switch.
But if you get chronically, psychosocially stressed, you're going to compromise your health. So, essentially, we've evolved to be smart enough to make ourselves sick.
We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.
What does the frontal cortex do? Gratification postponement, executive function, long-term planning, and impulse control. Basically, it makes you do the harder thing.
Perhaps most excitingly, we are uncovering the brain basis of our behaviors - normal, abnormal and in-between. We are mapping a neurobiology of what makes us us.
Genes are rarely about inevitability, especially when it comes to humans, the brain, or behavior. They're about vulnerability, propensities, tendencies.
To out-group-members, oxytocin makes you crappier - less cooperative and more preemptively aggressive. It's not the luv hormone. It's the in-group parochialism/xenophobia hormone.
Get it wrong, and we call it a cult. Get it right, in the right time and the right place, and maybe, for the next few millennia, people won't have to go to work on your birthday.
The fascinating thing about our best and worst behaviors isn't the behavior itself - the brain tells the muscles to do something or other - big deal. It's the meaning of the behavior.
As long as experiencing your optimal level of good stress doesn't damage others, it's hard to objectively define where normal enjoyment of stimulation becomes adrenaline junkiehood.
Genes are important for understanding our behavior. Incredibly important - after all, they code for every protein pertinent to brain function, endocrinology, etc.
It's probably even the case that if you stoked up some Buddhist monks with tons of testosterone, they'd become wildly competitive as to who can do the most acts of random kindness.