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The great tragedy of science - the slaying of a beautiful hypothesis by an ugly fact.
The chess-board is the world, the pieces are the phenomena of the universe, the rules of the game are what we call the laws of Nature. The player on the other side is hidden from us.
And you very soon find out, if you have not found it out before, that patience and tenacity of purpose are worth more than twice their weight of cleverness.
What would become of the garden if the gardener treated all the weeds and slugs and birds and trespassers as he would like to be treated, if he were in their place?
It is wrong for a man to say that he is certain of the objective truth of any proposition unless he can produce evidence which logically justifies that certainty.
The improver of natural knowledge absolutely refuses to acknowledge authority, as such. For him, skepticism is the highest of duties; blind faith the one unpardonable sin.
Men can intoxicate themselves with ideas as effectually as with alcohol or with bang and produce, be dint of serious thinking, mental conditions hardly distinguishable from monomania.
If a man cannot do brain work without stimulants of any kind, he had better turn to hand work it is an indication on Nature's part that she did not mean him to be a head worker.
Sit down before fact as a little child, be prepared to give up every conceived notion, follow humbly wherever and whatever abysses nature leads, or you will learn nothing.