As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me.

I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important.

I remember I had scenes with Melinda McGraw in "Ides Of March" that I didn't have in "Video Vigilante," but I can't quite picture that other character. But it was Vancouver, and that year was crazy

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.

My most romantic job: I was a manager at Baskin-Robbins.

When I read the script for Will & Grace in 1998, I knew I was the only guy for the part.

I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition.

I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one.

I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

The thing you realize pretty quickly, though, is that being in front of an audience whose job it is to laugh is a big pressure if the writing is not hilarious.

As much as I loved [Al] Pacino and [Robert] De Niro and wanted to be a dramatic actor, I also grew up on sitcoms.

How you react when your back is against the wall will determine if you see what's actually over the wall.

I wanted to, um, apologize for earlier. I can't believe I did that. I didn't think it could be real and—” “Didn’t think what could be real?” …Your penguin.

Excess of love, did ye say? There was no excess, there was defect. She loved her son too little, not too much. If she had loved him more there'd be no difficulty.

I believe that if we had would keep our dirty, bloody, dollar-crooked fingers out of the business of these nations so full of depressed, exploited people, they will arrive at a solution of their own.

So it always is: when you escape to a desert the silence shouts in your ear.

Man will never reach the Moon, regardless of all future scientific advances.

There is no good theory of disease which does not at once suggest a cure.

The actual writing is what you live for. The rest is something you have to get through in order to arrive at the point.

The soul is never less alone than when it is alone with God.

Jude [Law] is really good at playing an obsessive. He has a very watchable quality when he's on a quest for something.