As long as experiencing your optimal level of good stress doesn't damage others, it's hard to objectively define where normal enjoyment of stimulation becomes adrenaline junkiehood.

Stress is not a state of mind... it's measurable and dangerous, and humans can't seem to find their off-switch.

We live well enough to have the luxury to get ourselves sick with purely social, psychological stress.

The purpose of science is not to cure us of our sense of mystery and wonder, but to constantly reinvent and reinvigorate it.

An open mind is a prerequisite to an open heart.

But if you get chronically, psychosocially stressed, you're going to compromise your health. So, essentially, we've evolved to be smart enough to make ourselves sick.

The less it is possible that something can be, the more it must be.

Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.

We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.

What does the frontal cortex do? Gratification postponement, executive function, long-term planning, and impulse control. Basically, it makes you do the harder thing.

If a rat is a good model for your emotional life, you're in big trouble.

It is the confession, not the Priest, that gives us absolution

I want to let her know though that all the nights sleeping beside her even the useless arguments were things ever splendid and the hard words I ever feared to say can now be said: I love you.

Vision is an important part of being a good editor, but so is teamwork and grace.

How can love survive in such a graceless age? The trust and self assurance that lead to happiness, they're the very things we kill.

I am more than what you bargained for and nothin less than real.

My job isn't about pursuing fame and then becoming an actor. It's about becoming an actor and if fame follows suit, that's fine.

Artists who have won fame are often embarrassed by it; thus their first works are often their best.

Im so not into being emaciated.

Do what's good for humans, modeled on how humans already do things; ignore what's convenient for computers.

The worst experience can bring out a person's deepest strength.