Genes are rarely about inevitability, especially when it comes to humans, the brain, or behavior. They're about vulnerability, propensities, tendencies.

Stress is not a state of mind... it's measurable and dangerous, and humans can't seem to find their off-switch.

We live well enough to have the luxury to get ourselves sick with purely social, psychological stress.

The purpose of science is not to cure us of our sense of mystery and wonder, but to constantly reinvent and reinvigorate it.

An open mind is a prerequisite to an open heart.

But if you get chronically, psychosocially stressed, you're going to compromise your health. So, essentially, we've evolved to be smart enough to make ourselves sick.

The less it is possible that something can be, the more it must be.

Essentially, we humans live well enough and long enough, and are smart enough, to generate all sorts of stressful events purely in our heads.

We all seek out stress. We hate the wrong kinds of stress but when it's the right kind, we love it - we pay good money to be stressed by a scary movie, a roller coaster ride, a challenging puzzle.

What does the frontal cortex do? Gratification postponement, executive function, long-term planning, and impulse control. Basically, it makes you do the harder thing.

If a rat is a good model for your emotional life, you're in big trouble.

If you don't kill all of us all at once, those who remain will not be the weak.It's the strong who remain, the bent but unbroken, like the iron rods that used to give this concrete its strength.

Life is fragile, handle with prayer.

Diligence, hard work, perseverance, excellence are the values that cause things to happen.

The beauty about being a producer is you sit there, and you explore ideas which become a passion, which slowly becomes a reality.

Sometimes I just crave to play in Shakespeare again and I know and love playing Orlando so much.

That stupid Charlie Brown! He had the nerve to say I'm not perfect!" "So I suppose you hit him, huh?" "Rats! I knew I forgot something!

Cities, like dreams, are made of desires and fears, even if the thread of their discourse is secret, their rules are absurd, their perspectives deceitful, and everything conceals something else.

Why is it illegal to park in a handicapped parking space but okay to go the bathroom in a handicapped stall?

The US presidency will continue to represent the major power groups of the United States - big business and the military - regardless of who the talking head is.

Whenever the people are well informed, they can be trusted with their own government; that whenever things get so far wrong as to attract their notice, they may be relied on to set them to rights.