Hope differs from optimism. Hope does not arise from being told to "think positively," or from hearing an overly rosy forecast. Hope, unlike optimism, is rooted in unalloyed reality.

Hope gives us the courage to confront our circumstances and the capacity to surmount them.

I had learned that every patient has the right to hope, despite long odds, and it was my role to help nurture that hope.

False hope can lead to intemperate choices and flawed decision making. True hope takes into account the real threats that exist and seeks to navigate the best path around them.

Hope can be imagined as a domino effect, a chain reaction, each increment making the next increase more feasible... There are moments of fear and doubt that can deflate it.

There is an authentic biology of hope. Belief and expectation - the key elements of hope - can block pain by releasing the brain's endorphins and enkephalins, mimicking the effects of morphine.

Hope is the elevating feeling we experience when we see - in the mind's eye - a path to a better future.

True hope is cleareyed. It sees all the difficulties that exist and all the potential for failure, but through that carves a realistic path to a better future.

Even when there is no longer hope for the body, there is always hope for the soul.

On average, physicians interrupt patients within eighteen seconds of when they begin telling their story.

Hope, true hope, has proved as important as any medication I might prescribe or any procedure I might perform.

I guess what I'm trying to say is that you are there, in everything I am, in everything I've ever done, and looking back, I know that I should have told you know much you've always meant to me.

Success does not judge one man for being worthy above another. Success doesn’t choose you because of your family name or existing wealth.

Because I think that by beauty, you don't just mean something that's pretty. You mean something that makes us human.

He told himself that he could die some other time, in some other place.

Voter: someone smart enough to choose how to be fooled.

What’s burning?” “Your brain.

Those of you that will be 21 by November the 12th, I ask for your support and your vote.

You dance inside my chest, where no one sees you.

As you awaken to your divine nature, you'll begin to appreciate beauty in everything you see, touch and experience.