I didn't have time. I was too busy breaking up Tom Cruise and Nicole Kidman's marriage. (on rumours he was responsible for Julia Roberts and Benjamin Bratt's break-up)

There is a strange pecking order among actors. Theatre actors look down on film actors, who look down on TV actors. Thank God for reality shows, or we wouldn't have anybody to look down on.

After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

Peace is a fulltime job. It's protecting civilians, overseeing elections, and disarming ex-combatants. Peace, like war, must be waged.

I don't believe in happy endings, but I do believe in happy travels, because ultimately, you die at a very young age, or you live long enough to watch your friends die. It's a mean thing, life.

Life’s better with company. Everybody needs a co-pilot.

If you don't drink coffee, I am suspicious of your character and will not invite you to my Italian lake home.

I had to stop going to auditions thinking, 'Oh, I hope they like me.' I had to go in thinking I was the answer to their problem.

The truth of the matter is the real story are the people who rise above all of this incredible cruelty. Otherwise that cruelty wins.

Failures are infinitely more instructive than successes.

I'm a Method actor. I spent years training for the drinking and carousing I had to do in this film.

Orrin Hatch is old enough to be my father, and I don't want my father running the United States Senate Finance Committee.

If you watch Two and a Half Men, please stop watching Two and a Half Men. I'm on Two and a Half Men and I don't want to be on it. Please stop watching it. Please stop filling your head with filth.

In Cookie's defense, it was raining wildcats and rabid dogs.

Could I make you believe something that wasn't true?' He studied her through his eyelashes. 'You could make me believe anything at all.

Nothing distinguishes more clearly conditions in a free country from those in a country under arbitrary government than the observance in the former of the great principles known as the Rule of Law.

We know the IRS has made clear there is no prohibition on releasing it when you're under audit.

Bullies are just ignorant.

Kenya is risking sanctions from international competition because international organisations think we are not addressing the problem in line with world best practice.

Wishing is not acting. But willing is acting.

The earthly meaning of eternal life was death, and she refused to die.