I had run into Kari Lizer at an airport, I think, and she said, "Would you come on the show [ The New Adventures Of Old Christine]?" And I said, "God. Absolutely."

I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important.

I remember I had scenes with Melinda McGraw in "Ides Of March" that I didn't have in "Video Vigilante," but I can't quite picture that other character. But it was Vancouver, and that year was crazy

As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me.

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.

My most romantic job: I was a manager at Baskin-Robbins.

When I read the script for Will & Grace in 1998, I knew I was the only guy for the part.

I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition.

I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one.

I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

The thing you realize pretty quickly, though, is that being in front of an audience whose job it is to laugh is a big pressure if the writing is not hilarious.

I don't dwell on success. Maybe that's one reason I'm successful.

Truly things are better in general now, in America, than in the past.

The South may not always be right, but by God it's never wrong!

Health depends on being in harmony with our souls

I made the grandkids laugh. John Madden finally liked me!

My ancestors were Puritans from England. They arrived here in 1648 in the hope of finding greater restrictions than were permissible under English law at that time.

My report card always said, 'Jim finishes first and then disrupts the other students'.

The maxim that men are not to be praised before their death was invented by envy and too lightly adopted by philosophers.

But it was an ending.

If we don't start thinking big about the CO2 problem, we may miss our opportunity to stop a climate runaway that will trash the habitable parts of the earth.