I have a trophy case that contains all the action figures ever made of me. It also has items I've stolen from my movies, like three guns and holsters from 'Serenity'.

It costs nothing to say something kind. Even less to shut up altogether.

I don't expect anybody to know who I am.

My worst day is still a really good day. I complain, but I catch myself and count my blessings. I am truly blessed.

Improv as an actor makes you present in the moment. You listen, you're attentive. You're not acting so much as reacting, which is what you're doing in life all the time.

Thank God there is a such thing as hiatus. We got the first 'Dr. Horrible' done in six days, we banged it out.

I like to say there's certain things you can't take back: One of them is 'I love you,' and one of them is bullets.

Do something today you've been afraid to do. A decision based on fear is the wrong decision.

What turned me on to comedy was - well, first of all, I like being able to laugh, I like people who can make me laugh.

I think I've been really good at surrounding myself with really talented people. I've picked the right coattails to ride on.

I slowly came to realize that this job of being an actor, you spend most of your time looking for work. That is your job. Your job is auditioning. You spend very little of your time actually working.

Think about it. Every time you fail at a task you've actually learned something new. The question is "what?

I like a bit of spunk in a lady

Many of us wake up at the age of 40 one day, dreading going to work because we were forced to pick a career before we could legally buy a beer.

Silence is not our heritage but our destiny; we live where we want to live.

The relationship between [John] Adams and [Tomas] Jefferson was extraordinary. They differed on every conceivable issue, except on the Revolution and the love of their country.

Finding permanent and universal causes for misfortune is the practice of despair.

The camel has a single hump, The dromedary, two; Or else the other way around; I'm never sure. Are you?

The sensory world is the school, without which the human being would never come to the spirit.

We shouldn't just think about mammograms and self-exams and self-care once a year. It should be an ongoing thing.

...and it is a serious matter to destroy a man's faith without replacing it.