I remember I had scenes with Melinda McGraw in "Ides Of March" that I didn't have in "Video Vigilante," but I can't quite picture that other character. But it was Vancouver, and that year was crazy

I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important.

As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me.

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.

My most romantic job: I was a manager at Baskin-Robbins.

When I read the script for Will & Grace in 1998, I knew I was the only guy for the part.

I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition.

I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one.

I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

The thing you realize pretty quickly, though, is that being in front of an audience whose job it is to laugh is a big pressure if the writing is not hilarious.

As much as I loved [Al] Pacino and [Robert] De Niro and wanted to be a dramatic actor, I also grew up on sitcoms.

Mercy is the stuff you give to people that don't deserve it.

Regardless of what others may tell you, you only need two Mexican-Americans for a Mexican standoff.

Soldiers are citizens of death's grey land, drawing no dividend from time's tomorrows.

A lot of athletes have this sort of invincibility: [The jellyfish] should worry about me. I don't worry about them. I'll just swim right through them.

Every girl wants songs written about her. Even the most hardened tattoo-covered punk rock girl would love a nice ballad written for her.

Sometimes love means not being able to bear seeing the one you love the way they are, when they're not what you hoped for them.

Humanity in its basic form is co-humanity.

He's fantastic on the ground but obviously he is very tall. (on Peter Crouch)

The friendship of a great man is a favor of the gods.

People talk over and over about bodhichitta, but so often their heart is quite cold.