I was just a guy who did adult or alternative comic books. And then suddenly to be, like, a New Yorker cover artist was a different thing.

The experience of reading a comic should not be the time it takes to turn each page.

There are certain artists and filmmakers who, I get the impression, are trying to show off how bad their characters can be, how immoral their characters can be.

I think when I finally got it in my head that I was going to do the story, I wanted to avoid doing what I thought people wanted me to do.

A lot of the kinship that people notice is not coincidental. I was very impressionable and trying to find my role models when I was twelve or thirteen.

I'm getting to a point in my life where my whole attitude about the relationship between myself and the audience is totally different.

If you're changing diapers and going to the playground, any ambitions of being a cool guy have to fly out the window.

I feel like if people are going to go to the effort to get a stamp and, you know, put it on an envelope that, you know, it's a big effort these days. So I often write back.

I started publishing my comic while I was still living with my parents.

When email and the Internet came along, I never publish an email address. I just stuck with this P.O. Box address.

For me, like, the more interesting a letter is I just get more excited and I know that this going to be great for my friends who are looking forward to reading that in my comic.

Be inspire to explore your world.

...freedom only gives you something to be sorry for.

If a woman gets insomnia, you never know where you're going to find her furniture the next morning. It's primal. We have so little we can control, but we can perfect the way our room looks.

A buddy will keep you honest and add a dimension of fun to your workout.

Failure to love is almost like murder.

It's hard to explain why I like Europe so much.

[When asked if her husband was still living:] It's a matter of opinion.

There is nothing like literature: I lose a cow, I write about her death, and my writing pays me enough to buy another cow.

When you're generating your own stuff, you can never have too much money around, because you've already sacrificed so much and cut your budget so much that everything's taking a hit.

Friendships come and go, but families are forever.