I would cancel dialysis to be in the [hopefully upcoming Firefly] movie.

It costs nothing to say something kind. Even less to shut up altogether.

I don't expect anybody to know who I am.

My worst day is still a really good day. I complain, but I catch myself and count my blessings. I am truly blessed.

Improv as an actor makes you present in the moment. You listen, you're attentive. You're not acting so much as reacting, which is what you're doing in life all the time.

Thank God there is a such thing as hiatus. We got the first 'Dr. Horrible' done in six days, we banged it out.

I like to say there's certain things you can't take back: One of them is 'I love you,' and one of them is bullets.

Do something today you've been afraid to do. A decision based on fear is the wrong decision.

What turned me on to comedy was - well, first of all, I like being able to laugh, I like people who can make me laugh.

I think I've been really good at surrounding myself with really talented people. I've picked the right coattails to ride on.

I slowly came to realize that this job of being an actor, you spend most of your time looking for work. That is your job. Your job is auditioning. You spend very little of your time actually working.

Beyond all sciences, philosophies, theologies, and histories, a child's relentless inquiry is truly all it takes to remind us that we don't know as much as we think we know.

A piece of art that speaks to you can open windows in a room you hadn’t even known was dark.

In the fall, she knew it was Death who sweetened the apples.

Classical music requires an immense amount of concentration, and I don't know if I would've been that committed to that particular life.

Convictions are variable; to be always consistent is to be sometimes dishonest.

Man the life of a workaholic... You either on ya work or just workin on it.

How can we explain the perpetuity of envy--a vice which yields no return?

Being a world champion is something I'm already proud of and can take for the rest of my life.

Cyberspace is an accident of the real. Virtual reality is the accident of reality itself.

Want girls to let you put your fingers in certain places? Get a manicure.