If you start thinking that only your biggest and shiniest moments count, you're setting yourself up to feel like a failure most of the time.

Spaceflight isn't just about doing experiments, it's about an extension of human culture.

Our role is to develop techniques that allow us to provide emergency life-saving procedures to injured patients in an extreme, remote environment without the presence of a physician.

Don't let life randomly kick you into the adult you don't want to become

Almost everything worthwhile carries with it some sort of risk.

Decide in your heart of hearts what really excites and challenges you, and start moving your life in that direction

Every single day you're the result of what you did on the days prior.

Focus on the journey, not on arriving at a certain destination.

Remember, nobody changes the world on their own.

Every decision you make, from what you eat to what you do with your time tonight, turns you into who you are tomorrow and the day after that.

The cool things about space is when you put your pants on here, you can put them on two legs at a time.

When was the last time you read a book? The truth now. And picture books don't count-I mean something with print in it.

We have a Creator, a Father who is hands-on and loves us unconditionally!

The richest genius, like the most fertile soil, when uncultivated, shoots up into the rankest weeds.

We cannot continue to see the Middle East in the context of 9/11. We must see it in the context of 2011.

Wow, you're never allowed to sleep late again. You're crankier than a fat guy in stilettos.

No man can avail himself of the forces of his creative imagination, while dissipating them.

Step outside the guidelines of the official umpires and make your own rules and your own reality.

Those who are able to see beyond the shadows and lies of their culture will never be understood let alone believed by the masses.

The great will not condescend to take anything seriously.

Good luck, boss. Don't let'em turn you into horse meat! (Blackjack)