It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.

There is no scientific study more vital to man than the study of his own brain. Our entire view of the universe depends on it.

Unfortunately it makes the unambiguous determination of triplets by these methods much more difficult than would be the case if there were only one triplet for each amino acid.

A comparison between the triplets tentatively deduced by these methods with the changes in amino acid sequence produced by mutation shows a fair measure of agreement.

It is essential to understand our brains in some detail if we are to assess correctly our place in this vast and complicated universe we see all around us.

Trying to determine the structure of a protein by UV spectroscopy was like trying to determine the structure of a piano by listening to the sound it made while being dropped down a flight of stairs.

It has yet to be shown by direct biochemical methods, as opposed to the indirect genetic evidence mentioned earlier, that the code is indeed a triplet code.

You can do reverse engineering, but you can’t do reverse hacking.

A final proof of our ideas can only be obtained by detailed studies on the alterations produced in the amino acid sequence of a protein by mutations of the type discussed here.

The dangerous man is the one who has only one idea, because then he'll fight and die for it.

It now seems very likely that many of the 64 triplets, possibly most of them, may code one amino acid or another, and that in general several distinct triplets may code one amino acid.

Being loved is the problem, because love is a demand - when you're loved, someone wants more of you.

Conventionality is not morality.

The will to work must dominate, for art is long and time is brief.

The Sopranos was the first show about the life of the writer. I never made any secret about the fact that it was about my mother.

Man is a masterpiece of creation if for no other reason than that, all the weight of evidence for determinism notwithstanding, he believes he has free will.

The purpose of polite behavior is never virtuous. Deceit, surrender, and concealment these are not virtues. The goal of the mannerly is comfort, per se.

I'm not that interested in female superheroes.

I realized then that I didn't understand anything. I read all the books I could.

Be bold and don't worry about what people think. They don't do it that often anyway.

Let the bucket of memory down into the well, bring it up. Cool, cool minutes. No one stirring, no plans. Just being there.