Now, a living organism is nothing but a wonderful machine endowed with the most marvellous properties and set going by means of the most complex and delicate mechanism.

It is what we know already that often prevents us from learning.

The experimenter who does not know what he is looking for will not understand what he finds.

When we meet a fact which contradicts a prevailing theory, we must accept the fact and abandon the theory, even when the theory is supported by great names and generally accepted.

Man can learn nothing unless he proceeds from the known to the unknown.

The terrain is everything; the germ is nothing.

Art is 'I'; science is 'we'.

A fact in itself is nothing. It is valuable only for the idea attached to it, or for the proof which it furnishes.

Those who do not know the torment of the unknown cannot have the joy of discovery.

Science increases our power in proportion as it lowers our pride.

All the vital mechanisms, varied as they are, have only one object, that of preserving constant the conditions of life in the internal environment.

To light a candle is to cast a shadow

May the New Year bring you new grace, new gladness and new glory.

There is nothing I can do that won’t bring me back to you.

An entire nation, it seemed, was standing in one long breadline, desperate for even the barest essentials. It was a crisis of monumental proportions. It was known as the Great Depression.

My wife is my closest friend. Sure, I'm attracted to her in every way possible, but that's not the answer. Because I've been attracted to other people, and I couldn't stand 'em after a while.

As far as I can work out, no-one really loses out.

I don't deal in frustration. I'm a fighter. And everything I've ever gotten, I've had to fight for.

Grace removes obstacles that we don’t even know are there. Grace is what arranges our lives so we are forced to look within.

The universe never did make sense; I suspect it was built on government contract.