Part of me thinks that innovation, real innovation in health care delivery, needs to happen from the bottom to the top.

The visionary starts with a clean sheet of paper, and re-imagines the world.

We don't know where our first impressions come from or precisely what they mean, so we don't always appreciate their fragility.

The great accomplishment of Jobs's life is how effectively he put his idiosyncrasies - his petulance, his narcissism, and his rudeness - in the service of perfection.

If everyone has to think outside the box, maybe it is the box that needs fixing.

The successful are those who have been given opportunities.

An aggressive drug-testing program would cut down on certain abuses, but its never going to catch everyone - or even close to everyone.

There will be statues of Bill Gates across the Third World. There's a reasonable shot that - because of his money - we will cure malaria.

Outlier are those who have been given opportunities-- -and who have had the strength and presence of mind to seize them.

When you're an underdog, you're forced to try things you would never otherwise have attempted.

If we are to learn to improve the quality of the decisions we make, we need to accept the mysterious nature of our snap judgments.

Happy birthday, Alexander, " Magnus murmured."Thanks for remembering, " Alec whispered back.

Every tomorrow has two handles. We can take hold of it with the handle of anxiety or the handle of faith.

And I am not one of these long-living fictional characters who prays for death as a release from the captivity of eternal life

I hate in-the-end kindnesses: they're about as nourishing as the third day of cold mutton.

It'd be really nice to wake up looking like, I don't know, Jake Gyllenhaal and think "Let's try this on for a day and see how it feels.

Bureaucracies are designed to perform public business. But as soon as a bureaucracy is established, it develops an autonomous spiritual life and comes to regard the public as its enemy.

It means you never know what's going to happen,' I said. 'You do your best, then take your chances. Everything else is beyond our control.

Of course I would change anything if John Cassavetes said so - it's his script. But he was very easy about that.

My, how beautiful is war! its songs, its leisure!

Real life isn't required to be logical, but fiction has to make sense.