Run for office? No. I've slept with too many women, I've done too many drugs, and I've been to too many parties.

There is a strange pecking order among actors. Theatre actors look down on film actors, who look down on TV actors. Thank God for reality shows, or we wouldn't have anybody to look down on.

After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

Peace is a fulltime job. It's protecting civilians, overseeing elections, and disarming ex-combatants. Peace, like war, must be waged.

I don't believe in happy endings, but I do believe in happy travels, because ultimately, you die at a very young age, or you live long enough to watch your friends die. It's a mean thing, life.

Life’s better with company. Everybody needs a co-pilot.

If you don't drink coffee, I am suspicious of your character and will not invite you to my Italian lake home.

I had to stop going to auditions thinking, 'Oh, I hope they like me.' I had to go in thinking I was the answer to their problem.

The truth of the matter is the real story are the people who rise above all of this incredible cruelty. Otherwise that cruelty wins.

Failures are infinitely more instructive than successes.

I'm a Method actor. I spent years training for the drinking and carousing I had to do in this film.

Medicine is as close to love as it is to science, and its relationships matter even at the edge of life itself.

...you suddenly realise that every chance of being the person you really wanted to be, is gone for ever, and the one you were, is the one those around you will remember.

I buy expensive suits. They just look cheap on me.

We rise and fall as one people, one nation.

Starry, starry night, flaming flowers that brightly blaze, swirling clouds in violet haze reflect Vincent's eyes of china blue.

I was not really as good as I should have been.

The pillow smells like the sunlight, a precious smell.

If you are a student, try to be a teacher; if you are a teacher, try to be a student!

I came back once or twice a year to visit my family, and then I would take off again. In the beginning, I think everybody thought I would get over it and get it out of my system. And I never did.

The bitter past, more welcome is the sweet.