The three main leads [in Townies] were Lauren [ Graham] and Jenna [Elfman] and Molly [Ringwald], and then Ron Livingston was on it as well. There was a lot of people to write funny stuff for.

I'm doing a very funny show in which we talk about issues. I speak at Aids charities and things. It's great to do something fun with our days and yet we're told we're doing something important.

I remember I had scenes with Melinda McGraw in "Ides Of March" that I didn't have in "Video Vigilante," but I can't quite picture that other character. But it was Vancouver, and that year was crazy

As a television actor, there's a power you're given to use your image to do something valuable. As a parent, these messages are particularly important to me.

The Andromeda strain is a killer disease that they've got to prevent from spreading to being 100 percent contagious. It's another one where we're racing to save humanity.

My most romantic job: I was a manager at Baskin-Robbins.

When I read the script for Will & Grace in 1998, I knew I was the only guy for the part.

I always get a little uppity when I hear the phrase 'TV actor.' It's like saying you're a magazine reporter. I was in the theater for ten years before I ever had a TV audition.

I was raised on 'Get Smart' and 'All in the Family' and 'M.A.S.H.,' and certainly when 'Cheers' came along, that was a big one.

I think we all realize that anyone can - and has - gotten AIDS. So there's obviously still a lot to be done.

The thing you realize pretty quickly, though, is that being in front of an audience whose job it is to laugh is a big pressure if the writing is not hilarious.

It's much easier to not know things sometimes. Things change and friends leave. And life doesn't stop for anybody.

Why does watching a dog be a dog fill one with happiness?

Old ideas can sometimes use new buildings. New ideas must use old buildings.

There is a driving force more powerful than steam, electricity and nuclear power: the will.

I think there is beauty in everything.

Texas Senator Ted Cruz announced he is running for president. Ted Cruz was born in Canada, his father fled to the United States from Cuba, and yet Ted Cruz is against immigration. Isn't that odd?

The way for the Palestinians to get a state is to go ahead and build it.

The Wacken festival started more than 20 years ago with just a few hundred people in attendance. Tickets now sell out before the lineup is announced.

They portray me as all these crazy things and I'm so not like that. I don't have entourages, I'm as normal as you can get in this lifestyle.

I’ve heard it said: ‘By his home you shall know him’; and we all know that we must pay attention to anyone who reverses the subject and auxiliary verb in his sentence.