We like our archetypes and heroes to be what they are at face value. And life doesn't work out like that

Unfortunately, overall, movies are a conglomerate. People buy and sell people in this business, which can get really ugly.

I love to rescue animals.... The pounds were so crowded they were putting animals down almost immediately. Seven thousand dogs were put to sleep.

I wanted to go to Jupiter. That was my plan from day one, and David Lynch gave me the ticket.

The really courageous and bold thing is to make movies about human behaviour

If my career were a hairstyle, it would be helmet-head.

Whatever character you play, it gives you the chance to expose another side of yourself that maybe you've never felt comfortable with, or never knew about

What do you say when someone has truly inspired you? How do you express to an artist how deeply their work has affected you?

You don't have to run away from life your whole life. You can really live. You can change. And you can be an agent of change.

There is so much in the world to care about.

I'm interested in human nature. That's why I chose to become an actor. Whatever people are struggling with, the struggle is often where the drama is.

Editas Medicine has an exclusive multimillion-dollar license with Juno Therapeutics to develop T cell therapies

The best way to become poor is to give nothing.

The dirty nurse, Experience, in her kind Hath fouled me.

To believe in Christ is to give your heart to Christ, which means not to affirm things about Christ, but it's like what you mean when you say, "I believe in my friend."

When you get ready to write your novel, outline it first. There's nothing worse than getting halfway through and realizing you've painted yourself in a plot corner.

Sometimes you tell someone to never call you again; and then the phone rings and you hope it's them - it's the most twisted logic of all time.

It is only in the mountains that I can fully appreciate my existence as a man in America, and my own native land

If you wait until circumstances justify your thinking pleasant thoughts, you are likely to wait forever.

It's the sheer joy of seeing things grow and helping them to grow, even harvesting the stuff that you've grown yourself, no matter how old you are.

There is nothing to do, just be. Do nothing. Be. No climbing mountains and sitting in caves. I do not even say "be yourself" since you do not know yourself. Just be.