Whatever you do, don’t wake up at 65 years old and think about what you should have done with your life.

There is a strange pecking order among actors. Theatre actors look down on film actors, who look down on TV actors. Thank God for reality shows, or we wouldn't have anybody to look down on.

After doing One Fine Day and playing a pediatrician on ER, I'll never have kids. I'm going to have a vasectomy.

Peace is a fulltime job. It's protecting civilians, overseeing elections, and disarming ex-combatants. Peace, like war, must be waged.

I don't believe in happy endings, but I do believe in happy travels, because ultimately, you die at a very young age, or you live long enough to watch your friends die. It's a mean thing, life.

Life’s better with company. Everybody needs a co-pilot.

If you don't drink coffee, I am suspicious of your character and will not invite you to my Italian lake home.

I had to stop going to auditions thinking, 'Oh, I hope they like me.' I had to go in thinking I was the answer to their problem.

The truth of the matter is the real story are the people who rise above all of this incredible cruelty. Otherwise that cruelty wins.

Failures are infinitely more instructive than successes.

I'm a Method actor. I spent years training for the drinking and carousing I had to do in this film.

You can speak to me like you haven’t spoken even to yourself.

Nothing of worthy or weight can be achieved with half a mind with a faint heart and with a lame endeavor.

The fact my relationship with my son is so good makes me forgiving of my father and also appreciative.

We have a system that's really founded on profit and on selling pharmaceuticals as opposed to keeping people healthy and then helping them get back to health.

We're all pretty ordinary on paper.

You don't need to be a scientist to know Earth's age or that life evolved. You just need be one who embraces objective truths

If you don't have the roots somewhere, it's very difficult for people to work with you. Because you are a different person from them. They don't know you, really. They don't know how you feel.

If your enemy is superior, evade him

At one time if you were a black writer you had to be one of the best writers in the world to be published. You had to be great. Now you can be good. Mediocre. And that's good.

I would not wear any clothes that had a brand name on them, and I only read books that were canonical.