When you go out for drinks, tell people to bring in a news story that made them say "Oh my god." Talk about it.

Really life is about narcissism; no one is ever thinking about you much. You always think people are thinking about you way more than they are.

I'm not sure I'm okay with 2 guys gettin' married, but I don't wanna be a jerk about it.

And home pregnancy tests? They are so last century. Nowadays, I think there's an app that calls your iPhone to warn you that if you finish that third cosmo, you may wind up with a wombmate.

Every era in history has needed, and will need, reproductive health services.

You can't solve a problem until you address the problem.

By some fluke, my folks forgot to ask me the question most crucial to ensuring a lifetime of self-doubt: 'What if you fail?

We've got a deeply flawed political system with an insane overreaching extremist element, with a Supreme Court that is completely loony.

My curiosity is not a choice. It's always been part of me. I think of it as a vital organ.

I'm Catholic. My mother and I were unpacking and she found my diaphragm. I had to tell her it was a bathing cap for my cat.

Commit a little bit more to the world outside of your own life. Get people talking.

You learn almost as much about a thinker from what he reads—in particular, what he likes and what he disdains—as from what he writes himself.

Precipitate as weather, she appeared from somewhere then evaporated, leaving only memory.

All rising to great places is by a winding stair.

People were interesting at first. Then later, slowly but surely, all the flaws and madness would manifest themselves. I would become less and less to them; they would mean less and less to me.

If you can't be good, be good at it!

Obviously, David [Shore] probably has pressure because House was such an amazing show. But I try not to go into these jobs, thinking that I have to live up to people's expectations.

you'd definitely think of me more as a good sport than as an athlete.

Wit is the god of moments, but Genius is the god of ages.

To play a role where you get to reveal intellectual change is wonderful.

The trip across Arizona is just one oasis after another. You can just throw anything out and it will grow there, I like Arizona.