You know what you have to do, you just can't do it", Sara says wearily. "It's like you have bricks on your feet.

My training makes me uneasy with a happy mystery.

Theories without data are like daydreams.

Though I learned little in my compromised state, I learned enough to make a decision: I was going to understand how mood could overwhelm. I was going to understand depression or die trying.

One reason we're not winning the fight against depression is that our available treatments leave so many in partial recovery limbo.

Just as a stressful life can make you depressed, continuing exposure to stressors maintains depression.

Depressed people don't end up lying in bed because they are undercommitted to goals. They end up lying in bed because they are overcommitted to goals that are failing.

Life is like a rollercoaster. It has ups and downs. But it's your choice to scream or enjoy the ride.

If the fundamental principles in the Declaration of Independence, as self-evident truths, are real truths, the existence of slavery, in any form, is a wrong.

In the end, we would like not to be guilty while at the same time being dispensed of the effort of purifying ourselves. Not enough cynicism and not enough virtue.

You develop millionaires the way you mine gold. You expect to move tons of dirt to find an ounce of gold, but you don't go into the mine looking for the dirt-you go in looking for the gold.

They say I need to be seasoned; they say I need to be stewed. They say, 'We need to boil all the hope out of him -- like us -- and then he'll be ready.'

The body is held together by sound. The presence of disease indicates that some sounds have gone out of tune.

Throughout the time in which I am working on a canvas I can feel how I am beginning to love it, with that love which is born of slow comprehension.

Tatiana and the soldier were having a silence

I'm not planning on singing too late. Maybe another eight or 10 years is enough before I retire. It would also be great to revisit all these stunning places around the world where I have toured.

Remember, Republican economic policies quadrupled the debt before I took office and doubled it after I left. We simply can't afford to double-down on trickle-down.